Proteolytic activation of a bioactive cardiac peptide by in vitro trypsin cleavage.

Mammalian cardiac atria possess several unidentified biologically active peptides. Fractionation of rat atrial extracts by gel filtration chromatography revealed two major fractions [apparent molecular weights of 20,000-30,000 (peak I) and less than 10,000 (peak II)], both of which were potent natri...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Currie, M G, Geller, D M, Cole, B R, Needleman, P
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1984
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC344800/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6230673/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.4.1230
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