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A95 INFLAMMATORY PROTEASES DRIVE A MIGRATORY INTESTINAL EPITHELIAL PHENOTYPE THROUGH THE GENERATION OF BIOACTIVE PEPTIDE FRAGMENTS OF E-CADHERIN

BACKGROUND: The inflammatory microenvironment in the gut contains a variety of proteases which are known to be increased in patient samples in both IBD and CRC. How these proteases and their proteolytic peptide products contribute to wound resolution has been poorly elucidated. A cellular switch fro...

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Publié dans:J Can Assoc Gastroenterol
Auteurs principaux: Gordon, M, Chauvin, A, Boisvert, F, MacNaughton, W
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6508135/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwy009.095
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