ALDH2 Repression Promotes Lung Tumor Progression via Accumulated Acetaldehyde and DNA Damage()

The major role of aldehyde dehydrogenase 2 family (ALDH2) is to detoxify acetaldehyde (ACE) to non-toxic acetic acid. Many evidences suggest that ALDH2 dysfunction contributes to a variety of human diseases including cancer. However, the biological function and molecular mechanism of ALDH2 in tumor...

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Veröffentlicht in:Neoplasia
Hauptverfasser: Li, Kaimi, Guo, Wenzheng, Li, Zhanming, Wang, Yang, Sun, Beibei, Xu, Dongliang, Ling, Jing, Song, Hongyong, Liao, Yueling, Wang, Tong, Jing, Bo, Hu, Min, Kuang, Yanbin, Wang, Qi, Yao, Feng, Sun, Aijun, Zhu, Liang, Wang, Lishun, Deng, Jiong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Neoplasia Press 2019
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Original article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6506700/
https://ncbi.nlm.nih.gov/pubmed/31071657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2019.03.008
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