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Dietary Restriction Extends Lifespan Through Metabolic Regulation of Innate Immunity

Chronic inflammation predisposes to aging-associated disease, but it is unknown whether immunity regulation might be important for extending healthy lifespan. Here we show that in C. elegans, dietary restriction (DR) extends lifespan by modulating a conserved innate immunity pathway that is regulate...

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Detalhes bibliográficos
Publicado no:Cell Metab
Main Authors: Wu, Ziyun, Isik, Meltem, Moroz, Natalie, Steinbaugh, Michael J., Zhang, Peng, Blackwell, T. Keith
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6506407/
https://ncbi.nlm.nih.gov/pubmed/30905669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2019.02.013
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