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Genetic perturbation of key central metabolic genes extends lifespan in Drosophila and affects response to dietary restriction
There is a connection between nutrient inputs, energy-sensing pathways, lifespan variation and aging. Despite the role of metabolic enzymes in energy homeostasis and their metabolites as nutrient signals, little is known about how their gene expression impacts lifespan. In this report, we use P-elem...
Enregistré dans:
| Publié dans: | Proc Biol Sci |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Royal Society
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4614758/ https://ncbi.nlm.nih.gov/pubmed/26378219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rspb.2015.1646 |
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