The immunoproteasome catalytic β5i subunit regulates cardiac hypertrophy by targeting the autophagy protein ATG5 for degradation

Pathological cardiac hypertrophy eventually leads to heart failure without adequate treatment. The immunoproteasome is an inducible form of the proteasome that is intimately involved in inflammatory diseases. Here, we found that the expression and activity of immunoproteasome catalytic subunit β5i w...

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Detaylı Bibliyografya
Yayımlandı:Sci Adv
Asıl Yazarlar: Xie, Xin, Bi, Hai-Lian, Lai, Song, Zhang, Yun-Long, Li, Nan, Cao, Hua-Jun, Han, Ling, Wang, Hong-Xia, Li, Hui-Hua
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Association for the Advancement of Science 2019
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6506244/
https://ncbi.nlm.nih.gov/pubmed/31086810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aau0495
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