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Ablation of Immunoproteasome β5i Subunit Suppresses Hypertensive Retinopathy by Blocking ATRAP Degradation in Mice

Inflammation is associated with retinal diseases. Our recent data demonstrate that immunoproteasome catalytic subunit β2i contributes to angiotensin II (Ang II)-induced retinopathy in mice. Here, we investigated the role of another catalytic subunit β5i in regulating retinopathy and its underlying m...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Wang, Shuai, Li, Jing, Wang, Tong, Bai, Jie, Zhang, Yun-Long, Lin, Qiu-Yue, Li, Jing-min, Zhao, Qi, Guo, Shu-Bin, Li, Hui-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6953897/
https://ncbi.nlm.nih.gov/pubmed/31636038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2019.09.025
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