USP1 links platinum resistance to cancer cell dissemination by regulating Snail stability

Resistance to platinum-based chemotherapy is a common event in patients with cancer, generally associated with tumor dissemination and metastasis. Whether platinum treatment per se activates molecular pathways linked to tumor spreading is not known. Here, we report that the ubiquitin-specific protea...

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Detaylı Bibliyografya
Yayımlandı:Sci Adv
Asıl Yazarlar: Sonego, Maura, Pellarin, Ilenia, Costa, Alice, Vinciguerra, Gian Luca Rampioni, Coan, Michela, Kraut, Alexandra, D’Andrea, Sara, Dall’Acqua, Alessandra, Castillo-Tong, Dan Cacsire, Califano, Daniela, Losito, Simona, Spizzo, Riccardo, Couté, Yohann, Vecchione, Andrea, Belletti, Barbara, Schiappacassi, Monica, Baldassarre, Gustavo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Association for the Advancement of Science 2019
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6506239/
https://ncbi.nlm.nih.gov/pubmed/31086816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aav3235
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