CDK6 protects epithelial ovarian cancer from platinum‐induced death via FOXO3 regulation

Epithelial ovarian cancer (EOC) is an infrequent but highly lethal disease, almost invariably treated with platinum‐based therapies. Improving the response to platinum represents a great challenge, since it could significantly impact on patient survival. Here, we report that silencing or pharmacolog...

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Udgivet i:EMBO Mol Med
Main Authors: Dall'Acqua, Alessandra, Sonego, Maura, Pellizzari, Ilenia, Pellarin, Ilenia, Canzonieri, Vincenzo, D'Andrea, Sara, Benevol, Sara, Sorio, Roberto, Giorda, Giorgio, Califano, Daniela, Bagnoli, Marina, Militello, Loredana, Mezzanzanica, Delia, Chiappetta, Gennaro, Armenia, Joshua, Belletti, Barbara, Schiappacassi, Monica, Baldassarre, Gustavo
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5623833/
https://ncbi.nlm.nih.gov/pubmed/28778953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201607012
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