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Analysis and minimization of cellular RNA editing by DNA adenine base editors
Adenine base editors (ABEs) enable precise and efficient conversion of target A•T base pairs to G•C base pairs in genomic DNA with a minimum of by-products. While ABEs have been reported to exhibit minimal off-target DNA editing, off-target editing of cellular RNA by ABEs has not been examined in de...
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| Udgivet i: | Sci Adv |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Association for the Advancement of Science
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6506237/ https://ncbi.nlm.nih.gov/pubmed/31086823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aax5717 |
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