The use of pyrosequencing for detection of hemagglutinin mutations associated with increased pathogenicity of H5N1 avian influenza viruses in mammals

Hemagglutinin (HA) cleavage is critical for virulence of influenza viruses. The amino acid residue at the P6 position of the HA cleavage site (HACS) has been shown to be most variable and to have a direct correlation with the cleavage efficiency and pathogenicity of H5N1 avian influenza viruses (AIV...

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Dades bibliogràfiques
Publicat a:J Vet Diagn Invest
Autors principals: Wang, Chenxi, Zhang, Yongning, Bing, Guoxia, Zhang, Xuxiao, Wang, Caixia, Wang, Mingyang, Sun, Yipeng, Wu, Shaoqiang, Lin, Xiangmei, Pu, Juan, Liu, Jinhua, Sun, Honglei
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2018
Matèries:
Brief Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505906/
https://ncbi.nlm.nih.gov/pubmed/29633913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1040638718769951
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