The use of pyrosequencing for detection of hemagglutinin mutations associated with increased pathogenicity of H5N1 avian influenza viruses in mammals

Hemagglutinin (HA) cleavage is critical for virulence of influenza viruses. The amino acid residue at the P6 position of the HA cleavage site (HACS) has been shown to be most variable and to have a direct correlation with the cleavage efficiency and pathogenicity of H5N1 avian influenza viruses (AIV...

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Detalles Bibliográficos
Publicado en:J Vet Diagn Invest
Main Authors: Wang, Chenxi, Zhang, Yongning, Bing, Guoxia, Zhang, Xuxiao, Wang, Caixia, Wang, Mingyang, Sun, Yipeng, Wu, Shaoqiang, Lin, Xiangmei, Pu, Juan, Liu, Jinhua, Sun, Honglei
Formato: Artigo
Idioma:Inglês
Publicado: SAGE Publications 2018
Assuntos:
Brief Communications
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505906/
https://ncbi.nlm.nih.gov/pubmed/29633913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1040638718769951
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