Prevailing PA Mutation K356R in Avian Influenza H9N2 Virus Increases Mammalian Replication and Pathogenicity

Adaptation of the viral polymerase complex comprising PB1, PB2, and PA is necessary for efficient influenza A virus replication in new host species. We found that PA mutation K356R (PA-K356R) has become predominant since 2014 in avian H9N2 viruses in China as with seasonal human H1N1 viruses. The sa...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Virol
Asıl Yazarlar: Xu, Guanlong, Zhang, Xuxiao, Gao, Weihua, Wang, Chenxi, Wang, Jinliang, Sun, Honglei, Sun, Yipeng, Guo, Lu, Zhang, Rui, Chang, Kin-Chow, Liu, Jinhua, Pu, Juan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2016
Konular:
Pathogenesis and Immunity
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008101/
https://ncbi.nlm.nih.gov/pubmed/27384648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00883-16
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller