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Aplidin (plitidepsin) is a novel anti-myeloma agent with potent anti-resorptive activity mediated by direct effects on osteoclasts

Despite recent progress in its treatment, Multiple Myeloma (MM) remains incurable and its associated bone disease persists even after complete remission. Thus, identification of new therapeutic agents that simultaneously suppress MM growth and protect bone is an unmet need. Herein, we examined the e...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Delgado-Calle, Jesus, Kurihara, Noriyoshi, Atkinson, Emily G., Nelson, Jessica, Miyagawa, Kazuaki, Galmarini, Carlos Maria, Roodman, G. David, Bellido, Teresita
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505631/
https://ncbi.nlm.nih.gov/pubmed/31105871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26831
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