Á lódáil...

Calpain Inhibition Increases SMN Protein in Spinal Cord Motoneurons and Ameliorates the Spinal Muscular Atrophy Phenotype in Mice

Spinal muscular atrophy (SMA), a leading genetic cause of infant death, is caused by the loss of survival motor neuron 1 (SMN1) gene. SMA is characterized by the degeneration and loss of spinal cord motoneurons (MNs), muscular atrophy, and weakness. SMN2 is the centromeric duplication of the SMN gen...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:Mol Neurobiol
Main Authors: de la Fuente, Sandra, Sansa, Alba, Periyakaruppiah, Ambika, Garcera, Ana, Soler, Rosa M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Springer US 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505520/
https://ncbi.nlm.nih.gov/pubmed/30327977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-018-1379-z
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!