scNPF: an integrative framework assisted by network propagation and network fusion for preprocessing of single-cell RNA-seq data

BACKGROUND: Single-cell RNA-sequencing (scRNA-seq) is fast becoming a powerful tool for profiling genome-scale transcriptomes of individual cells and capturing transcriptome-wide cell-to-cell variability. However, scRNA-seq technologies suffer from high levels of technical noise and variability, hin...

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Bibliographic Details
Published in:BMC Genomics
Main Authors: Ye, Wenbin, Ji, Guoli, Ye, Pengchao, Long, Yuqi, Xiao, Xuesong, Li, Shuchao, Su, Yaru, Wu, Xiaohui
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
Subjects:
Methodology Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505295/
https://ncbi.nlm.nih.gov/pubmed/31068142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-019-5747-5
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