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scDAPA: detection and visualization of dynamic alternative polyadenylation from single cell RNA-seq data

MOTIVATION: Alternative polyadenylation (APA) plays a key post-transcriptional regulatory role in mRNA stability and functions in eukaryotes. Single cell RNA-seq (scRNA-seq) is a powerful tool to discover cellular heterogeneity at gene expression level. Given 3′ enriched strategy in library construc...

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Bibliografiska uppgifter
I publikationen:Bioinformatics
Huvudupphovsmän: Ye, Congting, Zhou, Qian, Wu, Xiaohui, Yu, Chen, Ji, Guoli, Saban, Daniel R, Li, Qingshun Q
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8215916/
https://ncbi.nlm.nih.gov/pubmed/31557285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btz701
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