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High-level extracellular production of recombinant nattokinase in Bacillus subtilis WB800 by multiple tandem promoters

BACKGROUND: Nattokinase (NK), which is a member of the subtilisin family, is a potent fibrinolytic enzyme that might be useful for thrombosis therapy. Extensive work has been done to improve its production for the food industry. The aim of our study was to enhance NK production by tandem promoters i...

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Dettagli Bibliografici
Pubblicato in:BMC Microbiol
Autori principali: Liu, Zhongmei, Zheng, Wenhui, Ge, Chunlei, Cui, Wenjing, Zhou, Li, Zhou, Zhemin
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505213/
https://ncbi.nlm.nih.gov/pubmed/31064343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-019-1461-3
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