High-level extracellular production of recombinant nattokinase in Bacillus subtilis WB800 by multiple tandem promoters

BACKGROUND: Nattokinase (NK), which is a member of the subtilisin family, is a potent fibrinolytic enzyme that might be useful for thrombosis therapy. Extensive work has been done to improve its production for the food industry. The aim of our study was to enhance NK production by tandem promoters i...

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Bibliographic Details
Published in:BMC Microbiol
Main Authors: Liu, Zhongmei, Zheng, Wenhui, Ge, Chunlei, Cui, Wenjing, Zhou, Li, Zhou, Zhemin
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505213/
https://ncbi.nlm.nih.gov/pubmed/31064343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-019-1461-3
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