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High-level extracellular production of recombinant nattokinase in Bacillus subtilis WB800 by multiple tandem promoters

BACKGROUND: Nattokinase (NK), which is a member of the subtilisin family, is a potent fibrinolytic enzyme that might be useful for thrombosis therapy. Extensive work has been done to improve its production for the food industry. The aim of our study was to enhance NK production by tandem promoters i...

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Detalhes bibliográficos
Publicado no:BMC Microbiol
Main Authors: Liu, Zhongmei, Zheng, Wenhui, Ge, Chunlei, Cui, Wenjing, Zhou, Li, Zhou, Zhemin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505213/
https://ncbi.nlm.nih.gov/pubmed/31064343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-019-1461-3
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