High-level extracellular production of recombinant nattokinase in Bacillus subtilis WB800 by multiple tandem promoters

BACKGROUND: Nattokinase (NK), which is a member of the subtilisin family, is a potent fibrinolytic enzyme that might be useful for thrombosis therapy. Extensive work has been done to improve its production for the food industry. The aim of our study was to enhance NK production by tandem promoters i...

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Bibliografiske detaljer
Udgivet i:BMC Microbiol
Main Authors: Liu, Zhongmei, Zheng, Wenhui, Ge, Chunlei, Cui, Wenjing, Zhou, Li, Zhou, Zhemin
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505213/
https://ncbi.nlm.nih.gov/pubmed/31064343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-019-1461-3
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