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A Chinese pedigree with Brown-Vialetto-Van Laere syndrome due to two novel mutations of SLC52A2 gene: clinical course and response to riboflavin

BACKGROUND: Brown-Vialetto-Van Laere Syndrome (BVVLS), a rare neurological disorder characterized by motor, sensory, and cranial neuronopathies, is mainly associated with defective riboflavin transporters encoded by SLC52A2 and SLC52A3 genes. Clinical outcomes have been shown to be improved signific...

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Publicat a:BMC Med Genet
Autors principals: Shi, Kaili, Shi, Zhen, Yan, Huifang, Wang, Xiaodong, Yang, Yanling, Xiong, Hui, Gu, Qiang, Wu, Ye, Jiang, Yuwu, Wang, Jingmin
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505200/
https://ncbi.nlm.nih.gov/pubmed/31064337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-019-0811-1
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