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A Chinese pedigree with Brown-Vialetto-Van Laere syndrome due to two novel mutations of SLC52A2 gene: clinical course and response to riboflavin

BACKGROUND: Brown-Vialetto-Van Laere Syndrome (BVVLS), a rare neurological disorder characterized by motor, sensory, and cranial neuronopathies, is mainly associated with defective riboflavin transporters encoded by SLC52A2 and SLC52A3 genes. Clinical outcomes have been shown to be improved signific...

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Detalhes bibliográficos
Publicado no:BMC Med Genet
Main Authors: Shi, Kaili, Shi, Zhen, Yan, Huifang, Wang, Xiaodong, Yang, Yanling, Xiong, Hui, Gu, Qiang, Wu, Ye, Jiang, Yuwu, Wang, Jingmin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505200/
https://ncbi.nlm.nih.gov/pubmed/31064337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-019-0811-1
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