Anti-EMT properties of CoQ0 attributed to PI3K/AKT/NFKB/MMP-9 signaling pathway through ROS-mediated apoptosis

BACKGROUND: Breast cancer is the most prevalent cancer among women. In triple-negative breast cancer (TNBC) cells, a novel quinone derivative, coenzyme Q(0) (CoQ(0)), promotes apoptosis and cell-cycle arrest. This study explored the anti-epithelial–mesenchymal transition (EMT) and antimetastatic att...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Yang, Hsin-Ling, Thiyagarajan, Varadharajan, Shen, Pei-Chun, Mathew, Dony Chacko, Lin, Kai-Yuan, Liao, Jiunn-Wang, Hseu, You-Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505074/
https://ncbi.nlm.nih.gov/pubmed/31068208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1196-x
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