In vitro and in vivo anti-tumor activity of CoQ(0) against melanoma cells: inhibition of metastasis and induction of cell-cycle arrest and apoptosis through modulation of Wnt/β-catenin signaling pathways

Coenzyme Q(0) (CoQ(0), 2,3-dimethoxy-5-methyl-1,4-benzoquinone), a novel quinone derivative, has been shown to modulate cellular redox balance. However, effect of this compound on melanoma remains unclear. This study examined the in vitro or in vivo anti-tumor, apoptosis, and anti-metastasis activit...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Hseu, You-Cheng, Thiyagarajan, Varadharajan, Tsou, Hsiao-Tung, Lin, Kai-Yuan, Chen, Hui-Jye, Lin, Chung-Ming, Liao, Jiuun-Wang, Yang, Hsin-Ling
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008369/
https://ncbi.nlm.nih.gov/pubmed/26968952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7983
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