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Off the street phasing (OTSP): no hassle haplotype phasing for molecular PGD applications

PURPOSE: Pre-implantation genetic diagnosis (PGD) for molecular disorders requires the construction of parental haplotypes. Classically, haplotype resolution (“phasing”) is obtained by genotyping multiple polymorphic markers in both parents and at least one additional relative. However, this process...

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Bibliografiska uppgifter
I publikationen:J Assist Reprod Genet
Huvudupphovsmän: Zeevi, David A., Zahdeh, Fouad, Kling, Yehuda, Carmi, Shai, Altarescu, Gheona
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer US 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504987/
https://ncbi.nlm.nih.gov/pubmed/30617673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-018-1392-1
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