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Off the street phasing (OTSP): no hassle haplotype phasing for molecular PGD applications

PURPOSE: Pre-implantation genetic diagnosis (PGD) for molecular disorders requires the construction of parental haplotypes. Classically, haplotype resolution (“phasing”) is obtained by genotyping multiple polymorphic markers in both parents and at least one additional relative. However, this process...

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Podrobná bibliografie
Vydáno v:J Assist Reprod Genet
Hlavní autoři: Zeevi, David A., Zahdeh, Fouad, Kling, Yehuda, Carmi, Shai, Altarescu, Gheona
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504987/
https://ncbi.nlm.nih.gov/pubmed/30617673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-018-1392-1
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