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Preimplantation genetic diagnosis (PGD) for nonsyndromic deafness by polar body and blastomere biopsy

PURPOSE: Development of an efficient and reliable PGD protocol for nonsyndromic deafness, by polar body (PB) and blastomere PGD. METHODS: The GJB2/GJB6 mutations along with 12 polymorphic markers were used in PGD analysis of blastomeres or polar bodies in 14 couples for 35 cycles. Marker informativi...

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Detalhes bibliográficos
Main Authors: Altarescu, Gheona, Eldar-Geva, Talia, Brooks, Baruch, Zylber-Haran, Edith, Varshaver, Irit, Margalioth, Ehud J., Levy-Lahad, Ephrat, Renbaum, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758950/
https://ncbi.nlm.nih.gov/pubmed/19728075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-009-9335-5
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