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Cell cycle– and genomic distance–dependent dynamics of a discrete chromosomal region
In contrast to the well-studied condensation and folding of chromosomes during mitosis, their dynamics during interphase are less understood. We deployed a CRISPR-based DNA imaging system to track the dynamics of genomic loci situated kilobases to megabases apart on a single chromosome. Two distinct...
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| Udgivet i: | J Cell Biol |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Rockefeller University Press
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6504907/ https://ncbi.nlm.nih.gov/pubmed/30846483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201807162 |
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