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Cell cycle– and genomic distance–dependent dynamics of a discrete chromosomal region

In contrast to the well-studied condensation and folding of chromosomes during mitosis, their dynamics during interphase are less understood. We deployed a CRISPR-based DNA imaging system to track the dynamics of genomic loci situated kilobases to megabases apart on a single chromosome. Two distinct...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Ma, Hanhui, Tu, Li-Chun, Chung, Yu-Chieh, Naseri, Ardalan, Grunwald, David, Zhang, Shaojie, Pederson, Thoru
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504907/
https://ncbi.nlm.nih.gov/pubmed/30846483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201807162
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