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Depletion of the Nucleolar Protein Nucleostemin Causes G1 Cell Cycle Arrest via the p53 Pathway

Nucleostemin (NS) is a nucleolar protein expressed in adult and embryo-derived stem cells, transformed cell lines, and tumors. NS decreases when proliferating cells exit the cell cycle, but it is unknown how NS is controlled, and how it participates in cell growth regulation. Here, we show that NS i...

詳細記述

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書誌詳細
主要な著者: Ma, Hanhui, Pederson, Thoru
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Cell Biology 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924810/
https://ncbi.nlm.nih.gov/pubmed/17494866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-03-0244
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