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Depletion of the Nucleolar Protein Nucleostemin Causes G1 Cell Cycle Arrest via the p53 Pathway

Nucleostemin (NS) is a nucleolar protein expressed in adult and embryo-derived stem cells, transformed cell lines, and tumors. NS decreases when proliferating cells exit the cell cycle, but it is unknown how NS is controlled, and how it participates in cell growth regulation. Here, we show that NS i...

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Autors principals: Ma, Hanhui, Pederson, Thoru
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924810/
https://ncbi.nlm.nih.gov/pubmed/17494866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-03-0244
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