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Depletion of the Nucleolar Protein Nucleostemin Causes G1 Cell Cycle Arrest via the p53 Pathway

Nucleostemin (NS) is a nucleolar protein expressed in adult and embryo-derived stem cells, transformed cell lines, and tumors. NS decreases when proliferating cells exit the cell cycle, but it is unknown how NS is controlled, and how it participates in cell growth regulation. Here, we show that NS i...

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Detalhes bibliográficos
Main Authors: Ma, Hanhui, Pederson, Thoru
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924810/
https://ncbi.nlm.nih.gov/pubmed/17494866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-03-0244
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