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Depletion of the Nucleolar Protein Nucleostemin Causes G1 Cell Cycle Arrest via the p53 Pathway
Nucleostemin (NS) is a nucleolar protein expressed in adult and embryo-derived stem cells, transformed cell lines, and tumors. NS decreases when proliferating cells exit the cell cycle, but it is unknown how NS is controlled, and how it participates in cell growth regulation. Here, we show that NS i...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The American Society for Cell Biology
2007
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1924810/ https://ncbi.nlm.nih.gov/pubmed/17494866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-03-0244 |
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