Naringenin Produces Neuroprotection Against LPS-Induced Dopamine Neurotoxicity via the Inhibition of Microglial NLRP3 Inflammasome Activation

Background: Parkinson's disease (PD) is the second most prevalent central nervous system (CNS) degenerative disease and characterized by slow and progressive loss of dopamine (DA) neurons in the midbrain substantia nigra. Microglia-mediated neuroinflammation has been considered as the major cen...

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Vydáno v:Front Immunol
Hlavní autoři: Chen, Ce, Wei, Yi-Zheng, He, Xue-Mei, Li, Dai-Di, Wang, Guo-Qing, Li, Jing-Jie, Zhang, Feng
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504827/
https://ncbi.nlm.nih.gov/pubmed/31118933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00936
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