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Quercetin hinders microglial activation to alleviate neurotoxicity via the interplay between NLRP3 inflammasome and mitophagy

Activated microglia are an important type of innate immune cell in the brain, and they secrete inflammatory cytokines into the extracellular milieu, exert neurotoxicity to surrounding neurons and are involved in the pathogenesis of many brain disorders. Quercetin (Qu), a natural flavonoid, is known...

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Bibliografiska uppgifter
I publikationen:Redox Biol
Huvudupphovsmän: Han, Xiaojuan, Xu, Tianshu, Fang, Qijun, Zhang, Huajun, Yue, Lijun, Hu, Gang, Sun, Lingyun
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8182123/
https://ncbi.nlm.nih.gov/pubmed/34082381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2021.102010
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