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Interplay Between NLRP3 Inflammasome and Autophagy

The NLRP3 inflammasome is cytosolic multi-protein complex that induces inflammation and pyroptotic cell death in response to both pathogen (PAMPs) and endogenous activators (DAMPs). Recognition of PAMPs or DAMPs leads to formation of the inflammasome complex, which results in activation of caspase-1...

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Détails bibliographiques
Publié dans:Front Immunol
Auteurs principaux: Biasizzo, Monika, Kopitar-Jerala, Nataša
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7583715/
https://ncbi.nlm.nih.gov/pubmed/33163006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.591803
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