Blockade of AMPA Receptor Regulates Mitochondrial Dynamics by Modulating ERK1/2 and PP1/PP2A-Mediated DRP1-S616 Phosphorylations in the Normal Rat Hippocampus

N-Methyl-D-aspartate receptor (NMDAR) and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) activations induce fast and transient mitochondrial fragmentation under pathophysiological conditions. However, it is still unknown whether NMDAR or AMPAR activity contributes to mitochond...

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Udgivet i:Front Cell Neurosci
Main Authors: Kim, Ji-Eun, Choi, Hui-Chul, Song, Hong-Ki, Kang, Tae-Cheon
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504797/
https://ncbi.nlm.nih.gov/pubmed/31118889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00179
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