Progesterone Receptor Attenuates STAT1-Mediated Interferon Signaling in Breast Cancer

Why some tumors remain indolent and others progress to clinical relevance remains a major unanswered question in cancer biology. Interferon signaling in nascent tumors, mediated by STAT1, is a critical step through which the surveilling immune system can recognize and destroy developing tumors. Here...

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Udgivet i:J Immunol
Main Authors: Goodman, Merit L., Trinca, Gloria M., Walter, Katherine R., Papachristou, Evangelia K., D’Santos, Clive S., Li, Tianbao, Liu, Qi, Lai, Zhao, Chalise, Prabhakar, Madan, Rashna, Fan, Fang, Markiewicz, Mary A., Jin, Victor X., Carroll, Jason S., Hagan, Christy R.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504603/
https://ncbi.nlm.nih.gov/pubmed/30936295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1801152
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