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Progesterone receptor promotes degradation of STAT2 to inhibit the interferon response in breast cancer

Type I (IFNα/β) interferon signaling represents a critical transduction pathway involved in recognition and destruction of nascent tumor cells. Downregulation of this pathway to promote a more immunosuppressed microenvironment contributes to the ability of tumor cells to evade the immune system, a k...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Walter, Katherine R., Balko, Justin M., Hagan, Christy R.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7199813/
https://ncbi.nlm.nih.gov/pubmed/32391191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2020.1758547
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