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Progesterone receptor promotes degradation of STAT2 to inhibit the interferon response in breast cancer

Type I (IFNα/β) interferon signaling represents a critical transduction pathway involved in recognition and destruction of nascent tumor cells. Downregulation of this pathway to promote a more immunosuppressed microenvironment contributes to the ability of tumor cells to evade the immune system, a k...

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Bibliografische gegevens
Gepubliceerd in:Oncoimmunology
Hoofdauteurs: Walter, Katherine R., Balko, Justin M., Hagan, Christy R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7199813/
https://ncbi.nlm.nih.gov/pubmed/32391191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2020.1758547
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