Progesterone promotes immunomodulation and tumor development in the murine mammary gland

BACKGROUND: Clinical studies have linked usage of progestins (synthetic progesterone [P4]) to breast cancer risk. However, little is understood regarding the role of native P4, signaling through the progesterone receptor (PR), in breast tumor formation. Recently, we reported a link between PR and im...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Werner, Lauryn R, Gibson, Katelin A, Goodman, Merit L, Helm, Dominika E, Walter, Katherine R, Holloran, Sean M, Trinca, Gloria M, Hastings, Richard C, Yang, Howard H, Hu, Ying, Wei, Junping, Lei, Gangjun, Yang, Xiao-Yi, Madan, Rashna, Molinolo, Alfredo A, Markiewicz, Mary A, Chalise, Prabhakar, Axelrod, Margaret L, Balko, Justin M, Hunter, Kent W, Hartman, Zachary C, Lange, Carol A, Hagan, Christy R
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2021
Assuntos:
Basic Tumor Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103939/
https://ncbi.nlm.nih.gov/pubmed/33958486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001710
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