Progesterone promotes immunomodulation and tumor development in the murine mammary gland

BACKGROUND: Clinical studies have linked usage of progestins (synthetic progesterone [P4]) to breast cancer risk. However, little is understood regarding the role of native P4, signaling through the progesterone receptor (PR), in breast tumor formation. Recently, we reported a link between PR and im...

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Vydáno v:J Immunother Cancer
Hlavní autoři: Werner, Lauryn R, Gibson, Katelin A, Goodman, Merit L, Helm, Dominika E, Walter, Katherine R, Holloran, Sean M, Trinca, Gloria M, Hastings, Richard C, Yang, Howard H, Hu, Ying, Wei, Junping, Lei, Gangjun, Yang, Xiao-Yi, Madan, Rashna, Molinolo, Alfredo A, Markiewicz, Mary A, Chalise, Prabhakar, Axelrod, Margaret L, Balko, Justin M, Hunter, Kent W, Hartman, Zachary C, Lange, Carol A, Hagan, Christy R
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2021
Témata:
Basic Tumor Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8103939/
https://ncbi.nlm.nih.gov/pubmed/33958486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001710
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