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Deletion of Biliverdin Reductase A in myeloid cells promotes chemokine expression and chemotaxis in part via a complement C5a-C5aR1 pathway
Biliverdin reductase A (BVR-A) is a pleotropic enzyme converting biliverdin (BV) to bilirubin (BR), and a signaling molecule that has cytoprotective and immunomodulatory effects. We recently showed that BV inhibits the expression of complement activation fragment 5a receptor (C5aR1) in 264.7 RAW mac...
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| Publicat a: | J Immunol |
|---|---|
| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6504595/ https://ncbi.nlm.nih.gov/pubmed/30952817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701443 |
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