A specific sequence in the genome of respiratory syncytial virus regulates the generation of copy-back defective viral genomes

Defective viral genomes of the copy-back type (cbDVGs) are the primary initiators of the antiviral immune response during infection with respiratory syncytial virus (RSV) both in vitro and in vivo. However, the mechanism governing cbDVG generation remains unknown, thereby limiting our ability to man...

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Pubblicato in:PLoS Pathog
Autori principali: Sun, Yan, Kim, Eun Ji, Felt, Sébastien A., Taylor, Louis J., Agarwal, Divyansh, Grant, Gregory R., López, Carolina B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504078/
https://ncbi.nlm.nih.gov/pubmed/30995283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007707
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