A specific sequence in the genome of respiratory syncytial virus regulates the generation of copy-back defective viral genomes

Defective viral genomes of the copy-back type (cbDVGs) are the primary initiators of the antiviral immune response during infection with respiratory syncytial virus (RSV) both in vitro and in vivo. However, the mechanism governing cbDVG generation remains unknown, thereby limiting our ability to man...

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Detalles Bibliográficos
Publicado en:PLoS Pathog
Main Authors: Sun, Yan, Kim, Eun Ji, Felt, Sébastien A., Taylor, Louis J., Agarwal, Divyansh, Grant, Gregory R., López, Carolina B.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2019
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504078/
https://ncbi.nlm.nih.gov/pubmed/30995283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007707
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