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Coordinated D-cyclin/Foxd1 activation drives mitogenic activity of the Sonic Hedgehog signaling pathway

Sonic Hedgehog (Shh) signaling plays key regulatory roles in embryonic development and postnatal homeostasis and repair. Modulation of the Shh pathway is known to cause malformations and malignancies associated with dysregulated tissue growth. However, our understanding of the molecular mechanisms b...

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Detalhes bibliográficos
Publicado no:Cell Signal
Main Authors: Fink, Dustin M., Sun, Miranda R., Heyne, Galen W., Everson, Joshua L., Chung, Hannah M., Park, Sookhee, Sheets, Michael D., Lipinski, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6503977/
https://ncbi.nlm.nih.gov/pubmed/29284139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2017.12.007
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