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Proteoglycan interactions with Sonic Hedgehog specify mitogenic responses
Sonic Hedgehog (Shh) has dual roles in vertebrate development, as it promotes progenitor cell proliferation and induces tissue patterning. Here we show mitogenic and patterning functions of Shh can be uncoupled from one another. Using a genetic approach to selectively inhibit Shh-proteoglycan intera...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2676236/ https://ncbi.nlm.nih.gov/pubmed/19287388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2287 |
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