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A novel fluorescent surfactant enhances the delivery of the Cas9 ribonucleoprotein and enables the identification of edited cells

In this report, we designed and synthesized a novel fluorescent single tailed surfactant (termed FEDS), which can disrupt endosomes, complex lipofectamine, and can also identify cells that have been transfected. FEDS was able to increase the gene editing efficiency of lipofectamine/Cas9 ribonucleopr...

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Bibliografiske detaljer
Udgivet i:Chem Commun (Camb)
Main Authors: Li, Jie, Røise, Joachim Justad, Zhang, Jingtuo, Yang, Jiaying, Kerr, D. Lucas, Han, Hesong, Murthy, Niren
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6503854/
https://ncbi.nlm.nih.gov/pubmed/30931453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9cc00261h
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