Conformationally Regulated Peptide Bond Cleavage in Bradykinin

Ion mobility and mass spectrometry techniques are used to investigate the stabilities of different conformations of bradykinin (BK, Arg(1)-Pro(2)-Pro(3)-Gly(4)-Phe(5)-Ser(6)-Pro(7)-Phe(8)-Arg(9)). At elevated solution temperatures, we observe a slow protonation reaction, i.e., [BK+2H](2+)+H(+) → [BK...

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書誌詳細
出版年:J Am Chem Soc
主要な著者: Fuller, Daniel R., Conant, Christopher R., El-Baba, Tarick J., Brown, Christopher J., Woodall, Daniel W., Russell, David H., Clemmer, David E.
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6503673/
https://ncbi.nlm.nih.gov/pubmed/30028131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b04751
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