Alternative Oxidase Attenuates Cigarette Smoke–induced Lung Dysfunction and Tissue Damage

Cigarette smoke (CS) exposure is the predominant risk factor for the development of chronic obstructive pulmonary disease (COPD) and the third leading cause of death worldwide. We aimed to elucidate whether mitochondrial respiratory inhibition and oxidative stress are triggers in its etiology. In di...

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Veröffentlicht in:Am J Respir Cell Mol Biol
Hauptverfasser: Giordano, Luca, Farnham, Antoine, Dhandapani, Praveen K., Salminen, Laura, Bhaskaran, Jahnavi, Voswinckel, Robert, Rauschkolb, Peter, Scheibe, Susan, Sommer, Natascha, Beisswenger, Christoph, Weissmann, Norbert, Braun, Thomas, Jacobs, Howard T., Bals, Robert, Herr, Christian, Szibor, Marten
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Thoracic Society 2019
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6503618/
https://ncbi.nlm.nih.gov/pubmed/30339461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2018-0261OC
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