Sodium Benzoate Attenuates Secondary Brain Injury by Inhibiting Neuronal Apoptosis and Reducing Mitochondria-Mediated Oxidative Stress in a Rat Model of Intracerebral Hemorrhage: Possible Involvement of DJ-1/Akt/IKK/NFκB Pathway

Intracerebral hemorrhage (ICH) is a devastating disease with high rates of mortality and morbidity. The aim of this study was to explore whether Sodium Benzoate (NaB) could reduce neural cell apoptosis and alleviate neurological deficits after ICH. To assess the therapeutic effects of NaB, first, we...

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Vydáno v:Front Mol Neurosci
Hlavní autoři: Xu, Weilin, Li, Tao, Gao, Liansheng, Lenahan, Cameron, Zheng, Jingwei, Yan, Jun, Shao, Anwen, Zhang, Jianmin
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6503040/
https://ncbi.nlm.nih.gov/pubmed/31114478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2019.00105
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