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Melatonin Protects Against Neuronal Apoptosis via Suppression of the ATF6/CHOP Pathway in a Rat Model of Intracerebral Hemorrhage

Neuronal apoptosis is an important factor accounting for the poor outcomes of intracerebral hemorrhage (ICH). This study first showed that inhibition of activating transcription factor 6 (ATF6) could alleviate secondary brain injury through anti-apoptosis after ICH in rats. Melatonin, ATF6 and CCAAT...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Xu, Weilin, Lu, Xiaoyang, Zheng, Jingwei, Li, Tao, Gao, Liansheng, Lenahan, Cameron, Shao, Anwen, Zhang, Jianmin, Yu, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156428/
https://ncbi.nlm.nih.gov/pubmed/30283292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00638
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