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Plin2-deficiency reduces lipophagy and results in increased lipid accumulation in the heart

Myocardial dysfunction is commonly associated with accumulation of cardiac lipid droplets (LDs). Perilipin 2 (Plin2) is a LD protein that is involved in LD formation, stability and trafficking events within the cell. Even though Plin2 is highly expressed in the heart, little is known about its role...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Mardani, Ismena, Tomas Dalen, Knut, Drevinge, Christina, Miljanovic, Azra, Ståhlman, Marcus, Klevstig, Martina, Scharin Täng, Margareta, Fogelstrand, Per, Levin, Max, Ekstrand, Matias, Nair, Syam, Redfors, Björn, Omerovic, Elmir, Andersson, Linda, Kimmel, Alan R., Borén, Jan, Levin, Malin C.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6502866/
https://ncbi.nlm.nih.gov/pubmed/31061399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43335-y
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